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At the age of 15, while studying for her nine O levels and later two more A levels, Mc Call sang professionally with a band; however when she was 19 she decided to go solo.
During this time she dated old family friend Eric Clapton, who also produced her demo music disc and helped her to try to crack the pop music world.
She was the Female Voice Dubber on the first series of Channel 4's Eurotrash in 1993, in 1995 she went on to host the ITV game show God's Gift (transmitted very late at night) and in 1998 went on to present the cult dating show Streetmate.
Mc Call presented every series of Big Brother UK from 2000-2010.
Dissatisfied with her near misses in the record industry, she gave up singing and took a job at Models 1 on the men's desk as a booker.
Davina became well known for her outgoing and excitable deliveries of news to the camera, commonly speaking in a conversation like way.Mc Call has also tried a hand at acting appearances in Sam's Game (2001), a Friends-style TV sitcom (also starring Irish comedian Ed Byrne), which was slammed by the critics and lasted only one series.She has also appeared in the Leigh Francis comedy sketch shows Bo Selecta and A Bear's Tail.She stated in an interview on Parkinson that she started smoking canabis and moved onto cocaine and heroin from there.She then went on to say that she believed it was thanks to her grandmother that she went clean.
Her relationship with her mother was a difficult one and she has said that her mother "should never have had kids" describing how she once left her, at the age of 12, in a nightclub on her own.